In order for you to play The Coma 2: Vicious Sisters on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
10.6.8 (64Bit)
Processor (CPU):
Core2Duo
Memory (RAM):
3 GB RAM
Graphics Card:
Any with hardware 3D acceleration
Storage:
2 GB available space
Sound Card:
Soundblaster / equivalent
In order to play The Coma 2: Vicious Sisters on macOS with maximum graphics settings, you need a computer with a configuration no worse than the following
Operating System:
Version 10.6.8 or above (64Bit)
Processor (CPU):
2.3 GHz Intel Core i5
Memory (RAM):
4 GB RAM
Graphics Card:
Nvidia / AMD GPU with 256 MB or more
Storage:
3 GB available space
Sound Card:
Soundblaster / equivalent