In order for you to play There Is No Game: Jam Edition 2015 on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
OS X Sierra 10.12+
Processor (CPU):
Dual Core with SSE2 instruction set support
Memory (RAM):
4 MB RAM
Graphics Card:
1024MB VRAM, Metal/OpenGL 3.2 (Intel HD 4000)
Storage:
120 MB available space
Sound Card:
Built In