In order for you to play Streets of Rage 4 on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
10.9 Mavericks or newer
Processor (CPU):
Intel Core 2 Duo E8400 | AMD Phenom II X4 965
Memory (RAM):
4 GB RAM
Graphics Card:
NVIDIA GeForce GTS 250
Storage:
8 GB available space