In order for you to play La-Mulana on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
OS X 10.7(Lion)
Processor (CPU):
Intel® Core 2 Duo 2.0 GHz
Memory (RAM):
2 GB RAM
Hard Drive:
500 MB available space
In order to play La-Mulana on macOS with maximum graphics settings, you need a computer with a configuration no worse than the following
Operating System:
OS X 10.11(El Capitan) or higher
Processor (CPU):
Intel® Core i5 2.4 GHz
Memory (RAM):
4 GB RAM
Hard Drive:
500 MB available space