In order for you to play Twilight Struggle: Red Sea on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
Mac OS X 10.13+
Processor (CPU):
Intel Core 2 Duo, 2.0GHz
Memory (RAM):
4 MB RAM
Graphics Card:
nVIDIA GeForce GTX 260 256mb or ATI Radeon HD 5670 256mb or Intel HD Graphics 4600
Storage:
500 MB available space
Sound Card:
Any