In order for you to play Sanctum 2 on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
OSX 10.7 or later
Processor (CPU):
1,4 GHz Intel i5, 2.0 GHz Intel Dual Core
Memory (RAM):
4 GB RAM
Graphics Card:
Intel HD Graphics 4000
DirectX®:
9.0c
Hard Drive:
4 GB Free Space
Sound:
DirectX 9.0c-compatible, 16-bit