In order for you to play Dota Underlords on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
Mac OS 10.13.6 or newer
Processor (CPU):
Intel i5, 2.4 Ghz or better
Graphics Card:
AMD GCN-based GPU, Nvidia Kepler-based GPU or newer, Intel HD 4000 or newer (requires Metal)
Network:
Broadband Internet connection
Storage:
5 GB available space