In order for you to play Deponia Doomsday on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
Mac OSX 10.7
Processor (CPU):
Intel 2 GHz Dual Core CPU
Memory (RAM):
2 GB RAM
Graphics Card:
ATI Radeon HD 4850 Series, Geforce 130 Series with at least 512 MB VRAM
Storage:
3500 MB available space
Sound Card:
16 bit
In order to play Deponia Doomsday on macOS with maximum graphics settings, you need a computer with a configuration no worse than the following
Operating System:
Mac OSX 10.11
Processor (CPU):
Intel 2.7 GHz Dual Core CPU
Memory (RAM):
4 GB RAM
Graphics Card:
ATI Radeon HD 6970 Series, Geforce 640M GT or higher
Storage:
3500 MB available space
Sound Card:
16 bit