In order for you to play SIMULACRA on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
MacOS X 10.13 High Sierra or newer
Processor (CPU):
Dual Core Processor or newer
Memory (RAM):
2 GB RAM
Graphics Card:
nVidia GeForce 8800 GT, AMD Radeon HD 2400, Intel HD or any OpenGL 2.0 compatible graphics card released from 2012 onwards
Storage:
500 MB available space