In order for you to play Prototype on Windows with minimal graphics settings, your computer must meet the following requirements
OS *:
Windows® XP (with Service Pack 3) or Windows Vista®
Processor (CPU):
Intel® Core™2 Duo 2.6 GHz or AMD Athlon™ 64 X2 4000+ or better
Memory (RAM):
Vista 2 GB RAM / XP 1 GB RAM
Graphics Card:
All NVIDIA® GeForce® 7800 GT 256 MB and better chipsets. All ATI Radeon™ X1800 256 MB and better chipsets
DirectX®:
Microsoft DirectX 9.0c
Hard Drive:
8GB of free hard drive space
Sound:
DirectX® 9.0c compliant sound card