In order for you to play Little Misfortune on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
Mac OS X 10.8
Processor (CPU):
Intel(R) Core(TM) i5-6300U CPU @ 2.5 GHz
Memory (RAM):
8 GB RAM
Graphics Card:
Intel(R) HD Graphics 520
Storage:
8 GB available space