In order for you to play Divinity: Original Sin 2 - Definitive Edition on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
macOS 10.13.6 High Sierra
Processor (CPU):
Core i5
Memory (RAM):
8 GB RAM
Graphics Card:
HD Graphics 5000 or Radeon R9 M290X
Storage:
20 GB available space
In order to play Divinity: Original Sin 2 - Definitive Edition on macOS with maximum graphics settings, you need a computer with a configuration no worse than the following
Operating System:
macOS 10.14.2 Mojave
Processor (CPU):
Core i5
Memory (RAM):
8 GB RAM
Graphics Card:
HD Graphics 630+ or Radeon R9 M390X or eGPU
Storage:
20 GB available space