In order for you to play Demetrios - The BIG Cynical Adventure on macOS with minimal graphics settings, your computer must meet the following requirements
Operating System:
OS X 10.10 (64 bit) or later
Processor (CPU):
1.5 GHz Dual Core
Memory (RAM):
2 GB RAM
Graphics Card:
Intel HD Graphics 4000, Nvidia or ATI card with at least 256MB VRAM
Storage:
600 MB available space